Reticulon 4 (RTN4) Peptide
RTN4
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN983312
Aperçu rapide pour Reticulon 4 (RTN4) Peptide (ABIN983312)
Antigène
Reticulon 4 (RTN4)
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-RTN4 antibody (Catalog #: ARP46813_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Reticulon 4 (RTN4)
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Sujet
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RTN4 belongs to the family of reticulons. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. RTN4 is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates.This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified.
Alias Symbols: ASY, NI220/250, NOGO, NOGO-A, NOGOC, NSP, NSP-CL, Nbla00271, Nbla10545, Nogo-B, Nogo-C, RTN-X, RTN4-A, RTN4-B1, RTN4-B2, RTN4-C
Protein Interaction Partner: RTN4IP1,UQCRC1,UQCRC2,BCL2,BCL2L1,BCL2,BCL2L1,CNTNAP1,COL4A3BP,CRMP1,FXR2,LRCH4,LRPAP1,MBP,NAPA,PLEKHF2,PRR13,RAB33A,RTN3,RTN4IP1,RTN4R,SPG21,TUBA4A,UQCRC1,UQCRC2,BCL2,BCL2L1,CNTNAP1,COL4A3BP,CRMP1,FXR2,KCNA1,KCNA2,LRCH4,LRPAP1,NAPA,PLEKHF2,PRR13,RAB33A,RTN3,RTN4IP1,RTN4R,SIRT2,SPG21,UQCRC1,UQCRC2,WWP1
Protein Size: 199 -
Poids moléculaire
- 22 kDa
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ID gène
- 57142
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NCBI Accession
- NM_007008, NP_008939
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UniProt
- Q7L7Q5
Antigène
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